The archaeological museum of Nafplio is housed in the imposing Venetian stone-built building that closes with its impressive size and its rigorous, symmetrical form on the western side of Syntagma Square. The building was built in 1713, during the period of the 2nd Venetian occupation, by the fleet predictor Augustine Sagredo as a warehouse of the fleet, according to the marble Latin inscription built on its facade. It is one of the most beautiful and best preserved buildings of the Venetian era in Greece.

The new permanent exhibition of the museum is being developed in two rooms of the same floor plan on the two floors of the building and is structured in thematic units that present the cultures developed in Argolida from the prehistory to the late antiquity.